Valentine’s Day Action Alert: Reach Out & Touch a Vivisector (via University of Florida)
Posted: February 14, 2011 Filed under: Uncategorized Leave a comment »
Every University Animal Testing Laboratory In The UK
Posted: February 13, 2011 Filed under: Uncategorized 7 Comments »Every University Animal Testing Laboratory In The UK
ABERDEEN
Foresterhill Animal House, Aberdeen Royal infirmary, University of Aberdeen, AB9 2ZD
mice
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB
Tel: 01224 716226
pigs, sheep, deer, rodents, primates, dogs (from Harlan)
Zoology Building, University of Aberdeen, Kings College campus, Tillydrone Avenue, Aberdeen, AB24 2TZ
voles breeding colony, rodents, Aqualab (upgraded 2002)
Medical School Animal House, IMS Building, University of Aberdeen, Cornhill Road, Foresterhill, Scotland, AB9 2ZD
rabbits, rats & breed rabbits
Marine Laboratory Aberdeen, Victoria Road, Aberdeen AB11 9DB
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ASTON UNIVERSITY (BIRMINGHAM)
School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET
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BANGOR
Brambell Building, University of Wales – Bangor, Deiniol Road, Bangor, Gwynedd, LL57 2UW
rodents, rabbits
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BATH
Department of Biology and Biochemistry, University of Bath, Quarry Road, Bath BA2 7AY
rodents & breeding
Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY
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BIRMINGHAM
Biomedical Services Unit, University of Birmingham, Edgbaston, Birmingham B15 2TT
(Central Animal House – holds rodents, dogs, primates)
also breeds rodents, but mainly buy from Charles River
School of Biosciences, University of Birmingham, Birmingham B15 2TT
ferrets (Highgate Farm), rodents, geese
Medical School, University of Birmingham, B15
Rodents & breeding
MRC Centre for Immune Regulation, Department of Immunology, The Medical School, University of Birmingham, B15 2TT
Rodents (BMSU & Harlan UK)
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BIRMINGHAM CITY
Division of Physiology, Faculty of Health, Birmingham City University, Baker Building, Franchise Street, Perry Barr, Birmingham, B42 2SU
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BRADFORD
University of Bradford, IPI Building, Basement Level, Bradford, West Yorkshire, BD7 1DP
Rodents, rabbits, guinea pigs
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BRIGHTON
University of Brighton, School of Pharmacy & Biomolecular Science, Top Floor, Cockcroft Building, Lewis Road, Moulsecoomb, Brighton, BN2 4GJ
Rodents
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BRISTOL:
School of Clinical Veterinary Science, Langford, Bristol, BS40 5DU
- Division of Farm Animal Science
- Health Protection Agency Foodborne Zoonoses Unit
- Dolberry Building
- Churchill Building
Dogs, rodents, farm animals, Chickens, cats
University of Bristol Medical School, Physiology and Pharmacy Dept, University Walk, Clifton, Bristol, BS8 1TD
- H floor freezers
rodents (Harlan UK & breed own)
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BRUNEL (UXBRIDGE)
Department of Biological Sciences, Brunel University, Uxbridge, Middlesex, UB8 3PH
rodents
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CAMBRIDGE
Cambridge Medical School, Downing Street, Cambridgeshire, CB2 1QW
500 primates at any one time
Babraham Institute, Babraham Research Campus, Cambridge, CB2 3AT
Farm animals, primates, rodents, dogs
University Biomedical Department, south Cambridge.
Department of Clinical Biochemistry, University of Cambridge, Hopkins Building, Building O, Downing Site, Cambridge CB2 1QW
rodents & breeding
Biological Sciences, School of the, 17 Mill Lane, Cambridge CB2 1RX
Department of Physiology Development & Neuroscience, Physiological Laboratory, Downing Street, Cambridge CB2 3EG
cows
Department of Clinical Neurosciences, Trinity Lane, Cambridge CB2 1TN
rodents
Cambridge University Farm, 207 Huntingdon Road, Girton, CB3 0LH
breeding
Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA
rodents
Experimental Psychology, Department of, Downing Street, Cambridge CB2 3EB
primates
Genetics, Department of, Downing Site, Downing Street, Cambridge CB2 3EH
rodents
Life Sciences, Graduate School of, 17 Mill Lane, Cambridge CB2 1RX
Zoology, Department of, Downing Street, Cambridge CB2 3EJ
Anaesthesia, Division of, Level 4, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QQ
rodents
Wellcome Trust/MRC Building, Addenbrooke’s Hospital Site, Hills Road, Cambridge CB2 0XY
rodents
MRC Cancer Cell Unit and University of Cambridge/Cancer Research UK, Department of Oncology, Hills Road, Cambridge CB2 0XZ
rodents
Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Box 289, Level 4, Addenbrooke’s Hospital, Cambridge CB2 0QQ
rodents
Molecular Biology, Laboratory of, MRC Centre, Hills Road, Cambridge CB2 0QH
rodents
Neurology Unit, Level 5 and 6, A Block, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QQ
rodents
Section of Neuroradiology, University Department of Radiology, Cambridge University School of Clinical Medicine, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QQ
pigs
Veterinary Medicine, Department of, Madingley Road, Cambridge CB3 0ES
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CARDIFF
School of Molecular and Medical Biosciences, 54 Park Place, Cardiff, CF10 3AT
rodents, pigs
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CENTRAL LANCASHIRE (PRESTON)
School of Pharmacy and Pharmaceutical Sciences, The Faculty of Science and Technology, University of Central Lancashire, Preston, PR1 2HE
Department of Biological Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE
rodents
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CHESTER
Department of Biological Sciences, University of Chester, Thomas Building, Parkgate Road, Chester, CH1 4BJ
Rodents
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COVENTRY
Animal house shared with University of Warwick, departments with animal labs:
Faculty of Health & Life Sciences, Richard Crossman Building, Priory Street, Coventry, CV1 5FB
Biomolecular and Sport Sciences, James Starley Building, CVI 5FB
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CUMBRIA
Share with the University of Central Lancashire
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DE MONTFORT (LEICESTER)
School of Life Sciences, Hawthorn Building, The Gateway, Leicester, LE1 9BH
rodents
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DUNDEE
College of Medicine, Dentistry and Nursing, Animal House, Level 5, Biomedical Research Institute, Ninewells Hospital and Medical School, Dundee DD1 9SY
rodents
School of Psychology, (old University Library), Dundee, DD1 4HN
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DURHAM
Psychology Department, Durham University, South Road, Durham, DH1 3LE
mice, rats
School of Biological and Biomedical Sciences, Durham University, Durham DH1 3LE
mice, rats, rabbits, fish, and frogs
breed rodents
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EAST ANGLIA (NORWICH)
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, NR4 7TJ
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EDINBURGH
Small Animal House [Block G] – 0131 650 6275
Large Animal House [Block F] – 0131 650 6276 / 07944826440
Easter Bush, Roslin, EH25 9RG
Roslin Institute, Dryden-Mountmarle, Roslin, Midlothian EH25 9PS
March Animal House, March Building, King’s Buildings, Edinburgh, EH9 3JF
Medical Microbiology Animal House, School of Biomedical Sciences, Hugh Robson Building, George Square, Edinburgh EH8 9XD
breeding – rodents
Ashworth Laboratories, King’s Buildings, West Mains Road, University of Edinburgh, Edinburgh, EH9 3JF
Rodents (From Harlan UK)
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EDINBURGH NAPIER
School of Life Sciences, Napier University, 10 Colinton Road, Edinburgh EH10 5DT
Sheep, rodents
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ESSEX
Department of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, Essex, CO4 3SQ
rodents
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Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, Wolfson Building, University of Glasgow, Glasgow G12 8QQ
rodents
Central Research Facility, Division of Immunology, Infection & Inflammation, University of Glasgow, Western Infirmary, Glasgow, G11 6NT
rodents
Department of Zoology, Rooftop Laboratories, Central Research Facilities, University of Glasgow, Glasgow
rodents (From Harlan UK)
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GREENWICH
Department of Psychology, University of Greenwich, Southwood Site, Avery Hill Road, Eltham, London SE9 2UG
School of Chemical and Life Sciences, Wellington Street, London SE18 6PF
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HERIOT WATT (EDINBURGH)
Department of Pharmacology, Syntex Research Centre, Heriot Watt University Research Park, Riccarton, Edinburgh, EH14 4AP
Aptuit (previously Quintiles), Heriot-Watt University Research Park South, Edinburgh, EH14 4AP
Land owned by the university – Primates, dogs, rodents
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HERTFORDSHIRE
School of Psychology, Neuroscience Research Unit, University of Hertfordshire, Hatfield, Herts AL10 9AB
rodents
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HULL
Medical Research Laboratory. Wolfson Building,. University of Hull, HU6 7RX
rodents & breed
Department of Psychology, University of Hull, Cottingham Road Hull HU6 7RX
Tel: 01482 346 311
rodent
PHLS & Centre for MR Investigations, Hull Royal Infirmary, Anlaby Road, Hull, HU3 2LZ
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IMPERIAL COLLEGE LONDON
Central Biomedical Services, Imperial College, Charing Cross Campus, St Dunstan’s Road, London W6 8RP
Mansard Building Roof, Imperial College London, Hammersmith Hospital Campus, Du Cane Rd., London, W12 ONN
rodents
Dept. of Infectious Diseases and Immunity, Imperial College London, Hammersmith Hospital Campus, Commonwealth Bldg., Du Cane Rd., London, W12 ONN
guinea pigs
Charing Cross and Westminster Medical School (CXWMS)
Primates, rodents
St. Mary’s Hospital Medical School
Primates, rodents
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KEELE UNIVERSITY (STAFFORDSHIRE)
Biology Dept, Huxley Building, Keele University, Keele, Staffordshire, ST5 5BG
Large animals
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LANCASTER
Biological Sciences Animal Unit, Lancaster University, Bailrigg, Lancaster, LA1 4YQ
Work with animals at Lancaster is very limited
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LEEDS
Central Animal House, Top Floor, Worsley Building, Clarendon Way, University of Leeds, Leeds, LS2 9JT
Top Floor, Clinical Sciences, Building, St James’s University Hospital, Leeds LS9 7TF,
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LEICESTER
Biomedical Services Unit, MRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester, LE1 9HN
‘Top secret’ primate breeding unit, Transgenic rodents & breeding
Department of Cell Physiology & Pharmacology, Medical Sciences Building,
Maurice Shock Building & Henry Wellcome Building.
Department of Physiology, University of Leicester, Leicester LE1 9HN
Department of Genetics, University of Leicester, Leicester LE1 7RH
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LIVERPOOL
Central Animal House, School of Biological Sciences, Top Floor, University of Liverpool, Crown Street, Liverpool, L69 7ZB
breeding of transgenic rodents,
Unit of Reproductive Biology, University of Liverpool, Life Sciences Building, Crown Street, Liverpool L69 3BX
bats, rodent breeding colony (operated by Biochemistry Dept)
Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral CH64 7TE
dogs, including ex-racing greyhounds (Zig Zag Kennels) and mongrels, cats, rodents, farm animals
Brownlow Hill and Crown Street, Liverpool L69 7ZJ
Physiology Laboratory, Physiology Building, Crown Street, University of Liverpool, Liverpool L69 3BX
rodents
Liverpool Medical School, Top Floor, 150 Mount Pleasant, Liverpool, L69 3GD
dogs, rodents, primates
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LIVERPOOL JOHN MOORES
School of Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF
Research Institute for Sports and Exercise Sciences, Henry Cotton Campus, Liverpool John Moores University, L3 2ET
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:: UNIVERSITY OF LONDON (SUB-SCHOOLS AND UNIVERSITIES) ::
INSTITUTE OF CANCER RESEARCH (ICR)
15 Cotswold Rd, Belmont, Sutton Surrey SM2 5NG
primates, beagles, rodents
Chester Beatty Laboratories, Top Floor, 237 Fulham Road, London SW3 6JB
KING’S COLLEGE LONDON
Pharmaceutical Science Division, Franklin-Wilkins Building, King’s College London, 150 Stamford Street, London, SE1 9NH
primates, rodents
Department of Pharmacology & Therapeutics
Centre for Cardiovascular Biology and Medicine, King’s College, Guy’s Campus London, St Thomas’ Hospital, SE1 7EH
Beagles, rodents, rabbits
Division of Physiology, School of Biomedical Sciences, King’s College London, Guys Campus, London,
Dept of Psychology, Henriette Raphael Building, School of Biomedical Sciences, King’s College London, Guys Campus, London
Sackler Institute of Pulmonary Pharmacology, GKT School of Biomedical Sciences, 5th Floor Hodgkin Building, Guy’s Campus, King’s College London, London, SE1 1UL
LONDON SCHOOL OF HYGENE & TROPICAL MEDICINE
Animal House, 4th Floor, Keppel Street, London WC1E 7HT
Rodents, ferrets
ROYAL HOLLOWAY
School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX
rodents (from Harlan UK)
ROYAL VETERINARY SCHOOL (Conduct vivisection, not just holding animals for lessons)
Top Floor, Royal College Street, London, NW1 0TU
Cats, dogs, rodents
Clinical Veterinary Medicine, Royal Veterinary College Field Station, Hawkshead House, Hawkshead Lane, North Mymms, Hatfield, Herts, AL9 7TA
Horses
ST GEORGES U.O.L.
Biological Research Facilities, Faculty of Medicine and Biomedical Sciences, Cranmer Terrace, London, SW17 0RE
LONDON SCHOOL OF PHARMACY
Top Floor, University of London, 29-39 Brunswick Square, London, WC1N 1AX
Rodents and breeding, also have involvement with Guy’s Hospital animal labs
EASTMAN DENTAL INSTITUTE
Division of Microbial Disease, Eastman Dental Institute, 256 Gray’s Inn Road, London WC1X 8LD
rodents
ICR
Institute of Child Health, 30 Guildford Street, Bloomsbury, London, WC1
INSTITUTE OF NEUROLOGY
Institute of Neurology, Chandler House, 1 Wakefield Street London WC1N 1PJ
primates, cats
Medical Research Council’s Prion Unit, Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London , WC1N 3BG
rodents, cattle, sheep, goats
UNIVERSITY COLLEGE LONDON
Biotechnology and Biological Services, Research Council Centre for Structural Biology, University College London, London
Department of Anatomy and Developmental Biology and Centre for Neuroscience, University College London, Gower Street, London WC1E 6BT
Eisai London Research Laboratories Ltd. University College London, Bernard Katz Building, Gower Street, London, WC1E 6BT
rodents & breeding (Note: Have an injunction against animal rights activists)
Bloomsbury Institute of Intensive Care Medicine, Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT
rodents (From Charles River)
NIMR
The National Institute for Medical Research, The Ridgeway, Mill Hill, London , NW7 1AA
rodents, cats, primates, dogs, rabbits
Owned by MRC, however operated by University College London
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MANCHESTER
Stopford Building, 4th Floor (top), Manchester University Medical School, Oxford Road, Manchester, M13 9PT
rodents – Charles River, Jackson Laboratories
own breeding of rodents, guinea pigs also supply external, university of warwick
AV Hill Building, off Dover Street, Manchester, M13 9PL
rodents, beagles, pigs
Animal Services Unit, Paterson Institute for Cancer Research, Wilmslow Road, Withington, Manchester, M20 4BX
rodents and breeding
Manchester Interdisciplinary Biocentre, Henry Wellcome Building, Faculty of Life Sciences, 131 Princess Street, Manchester M1 7ND
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NEWCASTLE
The Medical School, Newcastle University, Henry Wellcome Building, Framlington Place, Newcastle upon Tyne, NE2 4HH
rodents & breeding, Guinea Pigs, Rabbits, primates
Division of Psychology, School of Biology and Psychology, Newcastle University, Henry Wellcome Building, Framlington Place, Newcastle upon Tyne, NE2 4HH
School of Agriculture, Food and Rural Development Agriculture Building, Newcastle University, Newcastle upon Tyne NE1 7RU
Pigs, Sheep, Cattle, birds
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NOTTINGHAM
Queens Medical Centre (QMC), Central Animal House, Top Floor, University of Nottingham Medical School, NG7 2UH
Rodents, primates, beagles
Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD
The School of Biology, The University of Nottingham, University Park, Nottingham, NG7 2RD
rodents & breeding
Department of Zoology, University of Nottingham, University Park, Nottingham, NG7 2RD
Rodents (From Harlan)
School of Psychology, The University of Nottingham, University Park, Nottingham, NG7 2RD
University Of Nottingham, Sutton Bonnington Campus, College Road, Sutton Bonington, Loughborough, Leicestershire LE12 5NT
Rodents, dogs, pigs, cattle, sheep
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NOTTINGHAM TRENT
School Of Animal, Rural & Environmental Sciences, Brackenhurst Farm, Nottingham Trent University, Brackenhurst Campus, Southwell, Nottinghamshire NG25 0QF
The John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS
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OPEN UNIVERSITY (MILTON KEYNES)
Department of Life Sciences, The Open University, Walton Hall, Milton Keynes, MK7 6AA
rodents
Department of Biology, The Open University, Walton Hall, Milton Keynes, MK7 6AA
breeding & rodents
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OXFORD (Note: Have an injunction)
Halifax House, South Parks Road, University of Oxford, OX1 3PS
Primates, rodents, fish
Department of Experimental Psychology, South Parks Road, University of Oxford, OX1 3PS
Primates, rodents, cats, aviary on roof
Laboratory of Developmental Physiology, Top Floor, John Radcliffe Hospital, Nuffleld Institute for Medical Research, University of Oxford, Oxford OX3 9DS
cattle, primates, rodents, cats
The Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital
Department of Biochemistry at the University of Oxford (roof)
Rodents & breeding
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS
Department ofAgricultural Science, University of Oxford, Parks Road, Oxford 0X1 3PF
Sir William Dunn School Of Pathology, South Parks Road, Oxford, OX1 3RE
rabbit unit
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OXFORD BROOKES:
School of Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford, OX3 0BP
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PLYMOUTH
School of Psychology, University of Plymouth, Drake Circus, PLYMOUTH, Devon, PL4 8AA
Faculty of Science and Technology, University of Plymouth, Drake Circus, Plymouth, PL4 8AA
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PORTSMOUTH
School of Pharmacy and Biomedical Sciences, University of Portsmouth, St Michael’s Building, White Swan Road, Portsmouth, Hamps PO1 2DT
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QUEEN MARGARET (EDINBURGH)
Department of Clinical Neurosciences, Western General Hospital
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QUEEN’S UNIVERSITY (BELFAST)
School of Biology and Biochemsitry, Queen’s University of Belfast, Faculty of Science and Agriculture, 97 Lisburn Road, Belfast, BT9 7BL, IRELAND
School of Psychology, Queen’s University Belfast, University Road, Belfast, Northern Ireland, BT7 1NN
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READING
School of Psychology and Clinical Language Sciences, Earley Gate, Reading, RG6 6AL
Reading School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6UR
School of Biological Sciences, University of Reading, Whiteknights, Reading, RG6 6UR
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ROBERT GORDON (ABERDEEN)
School of Pharmacy & Life Sciences, The Robert Gordon University, Schoolhill, Aberdeen, AB10 1FR
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ROEHAMPTON
Roehampton University, School of Human and Life Sciences, Whitelands College, Holybourne Avenue, London, SW15 4JD
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ROYAL COLLEGE OF SURGEONS
The Royal College of Surgeons of England, 35-43 Lincoln’s Inn Fields, London WC2A 3PE
rodents & breeding, rabbits
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SALFORD
School of Environment & Life Sciences, Peel Building, Salford Crescent, Manchester M5 4WT
Lankester Building Animal House, Salford Crescent, Manchester, M5 4WT
rodents, dogs & large animals
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SHEFFIELD
University of Sheffield Medical School, Top Floor, Beech Hill Road, S10 2RX
cats, rodents & breeding
Department of Biomedical Science, University of Sheffield, Addison Building, Western Bank, Sheffield, S10 2TN
rodents & breeding
Department of Animal and Plant Sciences, Alfred Denny Building, University of Sheffield, Western Bank, Sheffield, S10 2TN
Rodents
Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN
Centre for Biomaterials and Tissue Engineering, The Kroto Research Institute, North Campus, University of Sheffield, Broad Lane, Sheffield, S3 7HQ
rabbit breeding colony
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SHEFFIELD HALLAM
Biomedical Research Centre, Division of Biomedical Sciences, School of Science and Maths, City Campus, Howard Street, Sheffield, S1 1WB
rats (From Eisai Research Laboratories, London)
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SOUTHAMPTON
School of Biomedical Sciences Building Animal House, University of Southampton, Bassett Crescent East, Southampton, SO16 7PX
Rats (purchased from Harlan UK), breeding of GM mice
Department of University Medicine, University of Southampton, Level D, South Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD
Rodents & breeding
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ST. ANDREW’S (FIFE)
School of Psychology, University of St. Andrews, St. Andrews, KY16 9TS
primates, rodents
Department of Biology and Pre-clinical Medicine, University of St. Andrews, Fife, KY16 9TS
rodents
Gatty Marine Laboratory, School of Biology, University of St Andrews, St Andrews, Scotland, KY16 8LB
Fish
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STIRLING
Psychology Department, University of Stirling, Stirling, FK9 4LA
School of Biological and Environmental Sciences, University of Stirling, Stirling, FK9 4LA
Institute of Aquaculture, University of Stirling, Scotland, FK9 4LA.
Niall Bromage Freshwater Research Facility, Takmadoon Road, Buckieburn, near Carron Bridge, FK6 5JJ
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STRATHCLYDE
Department of Physiology and Pharmacology, University of Strathclyde, Glasgow G4 0NR
Rodents (from Harlan UK)
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, The John Arbuthnott Building, 27 Taylor Street, Glasgow, G4 0NR
Rodents (from Harlan UK) & breed
University of Strathclyde, Royal College, 204 George Street, Glasgow G1 1XW
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, SGBS, 199 Cathedral Street, Glasgow G4 0QU
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SUNDERLAND
Sunderland Pharmacy School, University of Sunderland, The Science Complex, City Campus, Fleming Building, Wharncliffe Street, Sunderland, SR1 3SD
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SURREY
Medical School, AW Building, University of Surrey, Guildford, Surrey, GU2 7TE
Faculty of Health and Medical Science, Duke of Kent Building, University of Surrey, Guildford, Surrey, GU2 7TE
Nutritional Sciences/Biochemical Sciences, AY Building, University of Surrey, Guildford, Surrey, GU2 7TE
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SUSSEX
School of Life Sciences & Biology, John Maynard Smith (JMS) Building, University of Sussex, Falmer, Brighton, BN1 9QG
Guinea-pig breeding colony, rodents – CRL
Department of Psychology, University of Sussex, Falmer, Brighton, BN1 9QH
Birds
Trafford Centre for Graduate Medical Education and Research, University of Sussex, Falmer, Brighton BN1 9RY
Rodents
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SWANSEA
Institute of Life Science, Swansea University, Singleton Park, Swansea, SA2 8PP
Neuroscience and Molecular Psychiatry (Conduct vivisection in ILS)
School of Medicine, Grove Building, University of Wales Swansea, Singleton Park, Swansea, SA2 8PP
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ULSTER
School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, Co. Londonderry, Ireland, BT52 1SA
Rodents & breeding
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UNIVERSITY OF WESTERN ENGLAND (UWE)
Animal Science Centre, Hartpury College, Hartpury House, Gloucester, GL19 3BE
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WARWICK
Department of Biological Sciences, Gibbet Hill Campus, Gibbet Hill Road, University of Warwick, Coventry, CV4 7AL
Warwick Medical School, Gibbet Hill Campus, Gibbet Hill Road, University of Warwick, Coventry, CV4 7AL
mice, breed for their use and supply Southampton University
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WOLVERHAMPTON
Division of Biomedical Sciences, University of Wolverhampton, City Campus – South, Wulfruna Street, Wolverhampton, WV1 1LY
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YORK
Department of Biology (Area 3), University of York, York YO10 5YW
Boris Johnson has approved plans for the UK Centre for Medical Research and Innovation (UKCMRI)
Posted: February 6, 2011 Filed under: Uncategorized Leave a comment »
There are plans to build a high level [3] virus containment facility & animal testing lab in Camden. The lab has been described as “becoming the world’s largest ever animal testing lab” & will be partially govt funded by 40 -50%. Currently Huntingdon Life Sciences near Cambridge is the third largest such European lab & the two labs could be in direct “competition” with each other say campaigners.
The Lab will bring together scientists from three leading biomedical research organisations to develop new treatments for illnesses such as cancer, heart disease and stroke, infections, and neurodegenerative diseases that affect families in the UK and around the world.
The roots of these and all diseases lie in the altered functioning of cells or the way they interact within the body. Developing a better understanding of biological processes in health will help us understand why disease develops and how it might be treated.
Progress in biomedical research is rapid, so UKCMRI’s research programme will not be defined in detail until closer to its opening in 2015.
Boris Johnson has approved plans for the UK Centre for Medical Research and Innovation (UKCMRI)
Key facts:
1500 staff, including 1250 scientists
Annual budget of over £100m
Initial investment of £600m (breakdown)
Thousand of animals will be tested on
Camden Councils Development Control committee by a majority of 4, voted in favour of granting planning permission to the UKCRMI.
The committee voted 8 in favour, 4 against
Against
Claire-Louise Leyland, Conservative (Belsize)
Paul Braithwaite, Liberal Democrat (Cantelowes)
Sean Birch, Labour (Gospel Oak)
Matt Sanders, Liberal Democrat (Haverstock).
For
Milena Nuti, Labour (Bloomsbury)
Sue Vincent, Labour (Holborn and Covent Garden)
Sarah Hayward, Labour (King’s Cross)
Roger Freeman, Conservative (Swiss Cottage)
Heather Johnson, Labour (Regent’s Park)
Andrew Marshall, Conservative (Swiss Cottage)
Gillian Risso-Gill, Liberal Democrat (West Hampstead)
Jenny Headlam-Wells, Labour (Kentish Town).
Scientists create ‘sick pigs’ to cure humans
Posted: February 4, 2011 Filed under: Uncategorized 1 Comment »Scientists create ‘sick pigs’ to cure humans
• Genetic modification has produced pigs that glow in blue light – now the Roslin scientists hope to use the technique to produce animals suffering from human diseases to aid research into cures. Picture: Complimentary/The Roslin Institute
The team of researchers is trying to produce pigs which are diseased with the lethal lung condition cystic fibrosis and an eye disease that leads to blindness in humans, The Scotsman has learned.
The highly controversial research is being carried out at the Roslin Institute in Edinburgh, famous for creating Dolly the cloned sheep. If the team is successful, the diseased animals would be used by drug companies to test potential new gene therapies for the conditions.
The cutting-edge research raises major ethical issues about harming animals intentionally for the benefit of humans. It has led to outrage from animal rights organisations.
In a frank interview with The Scotsman, Dr Bruce Whitelaw, head of developmental biology at the Roslin Institute, admitted he had struggled with the idea of creating diseased animals purely to try to benefit humans.
“We are saying we will make these animals sick purely for our benefit,” he admitted. However, he believes his team has a “moral right” to give the technique a try.
His work will be the subject of a debate tonight at Edinburgh Zoo on the ethics of genetically modifying animals.
Cystic fibrosis is an incurable hereditary condition that often leads to death in the early twenties. It is one of the most common life-threatening inherited diseases, affecting more than 8,500 people in the UK, including the son of the former prime minister, Gordon Brown.
Retinitis pigmentosa is the name given to a group of hereditary diseases of the eye, which affects about 25,000 people in the UK. It is a progressive genetic disease that eventually leads to blindness.
Dr Whitelaw said the pigs would be used as “models of the human diseases” to provide a better way to test potential treatments.
Existing options involve using mice, which he said were “inadequate”.
Dr Whitelaw believes there are theoretical reasons why pigs should be good models for human disease – because of many physical similarities, such as similar eye size.
However, he acknowledged that creating the diseased animals would “not necessarily” allow treatments to be developed.
But he said that, since the Roslin had managed to develop the techniques to modify the animals in this way, they should find out if it could help to find cures.
“We have this technology. It’s really important to try to see if it can help. It may not, in which case we should stop.
“I don’t think we should use this technology for something we can currently treat just so we can make the treatment slightly better, but we should use it for diseases that we don’t have treatments for,” he said.
He emphasised that, if the technique turned out not to be useful for finding treatments, he would be arguing “as strongly as anyone else” that it should no longer be used.
“But we should find out,” he added. “I believe we’ve got a moral right to find out.”
Dr Whitelaw believes it will take at least two years to produce the genetically modified pigs, and another two years to find out whether they could be treated.
He continued to justify the work by adding: “If we believe we need to have therapies for these diseases – and currently society en masse believes that – then we surely have to have that tested in the best way we can before it goes into that patient.
“Then the better the animal model – the more likely it’s going to tell you something about going into a human patient – the better.
“And basically mice are mediocre at best and the majority of studies are done on mice.”
The work at the Roslin Institute, which began last year, is unique in the UK.
So far, the scientists have not successfully created animals with the diseases.
The technique involves the use of viruses to carry chosen genes into fertilised eggs.
Once altered, the eggs are then implanted in surrogate females, so that theoretically animals are born with the genetic conditions.
The resulting pigs are a type of what is known as a transgenic animal – creatures that have inserted DNA that originated in a different species.
Already, to prove genes could be successfully inserted into animals using the technique, pigs have been produced at Roslin that carry a green fluorescent protein gene found naturally in jellyfish.
The animals have a greenish tinge in normal light and when viewed in blue light they glow. This was done to provide the scientists with a genetic marker – a physical manifestation of how the pigs had been modified.
The work at the Roslin Institute will be the subject of a debate called “After Dolly… where do you draw the line?” at Edinburgh Zoo tonight, when Dr Whitelaw will be joined by Peter Sandøe, professor of bioethics at the University of Copenhagen, Denmark.
Animal rights groups reacted with horror at the news.
Andrew Tyler, the director of Animal Aid, said the techniques involved the “intrusive, harmful, painful experiments on animals” and should be banned.
He also believes the science behind the research is flawed.
“This type of work leads to an enormous attrition rate of animals being born malformed or dying in the womb,” he said.
“The gene that is being added is being put in a different species and it interacts with all sorts of other genes so you cannot extrapolate from these altered animals to people.
“This should stop. It’s cruel and it’s scientifically fraudulent. It’s also fraudulent to the people who will think a cure is imminent, and it’s an intolerable imposition on the animals concerned.”
Dr Jarrod Bailey, scientific adviser for the British Union for the Abolition of Vivisection, argued that animals could not be used to predict whether a new treatment would be safe in people.
“Animal research is a failure. Around 100 Aids vaccines, over two dozen diabetes treatments and hundreds of treatments for stroke, Alzheimer’s, Parkinson’s, cancer and many more diseases – worked in mice, monkeys and even chimpanzees, yet failed in humans.
“Genetic modification has failed to overcome species differences at the root of these failures.”
And he added that it was cruel.
“Pigs have cognitive abilities more advanced than three-year-old children, ranking behind only dolphins and non-human primates,” he said.
Libby Anderson, political director at Advocates for Animals, said it made her “despair”.
“It’s depressing to hear this repeated focus on modified and mutated animals, when there is so much potential for non-animal research,” she said.
“It sounds like they are going down a blind alley, and even in the scientists’ mind it is clearly raising huge ethical issues.”
The Scottish SPCA was also opposed to the work, but chief superintendent Mike Flynn added that he acknowledged that “for the time being” animal testing was “required before essential medicines can be made available to relieve suffering in humans and animals”.
He added: “Thankfully, there have been improvements in this area in recent years and animals can only be used to help develop cures for life-threatening or debilitating disease.”
Experiments such as those taking place at the Roslin Institute are scrutinised by the Home Office Inspectorate and are licensed following consideration of the expected benefit and the welfare cost to the animals.
Dr Whitelaw told The Scotsman he was looking forward to hearing the views of the public at today’s debate.
“I think anyone is entitled to any opinion they have got,” he said. “I think the strength of a society is that we have grown-up debates and come to a conclusion. If society came to the conclusion that we shouldn’t do this, then I would accept that. I would think it was a wasted opportunity, but I would accept it.”
At the cutting edge of research
THE Roslin Institute was established in 1993 as a wholly-owned but independent institute of the Biotechnology and Biological Research Council (BBRC). Its antecedents, however, go back to 1919 and are closely linked to animal genetics research at the University of Edinburgh.
Its mission is to gain fundamental understanding of genetic, cellular, organ and systems bioscience underpinning common mechanisms of animal development and pathology, and to drive this into prevention and treatment of important veterinary diseases and develop sustainable farm animal production systems.
Based in the Midlothian village from where it takes its name, the institute is due to move next year to a £60.6 million facility currently under construction at the University of Edinburgh’s Easter Bush Veterinary campus.
In 1996, the institute won international fame and sparked ethical debate when Sir Ian Wilmut, Keith Campbell and their colleagues created Dolly the sheep, the first mammal to be cloned from an adult cell. Scientists cloned the ewe by inserting DNA from a single sheep cell into an egg before implanting it in a surrogate mother.
Three years ago, a Roslin team developed genetically modified chickens capable of laying eggs containing proteins needed to make cancer-fighting drugs.
Last year, scientists discovered genetic “brakes” which could slow down or stop diseases such as multiple sclerosis and cancer.
The study discovered that the way specific genes interact with one another is much more complicated than was previously thought.
The institute employs 68 research staff over five scientific divisions, and its current director is Professor David Hume.
Hogging the limelight in Africa
ANIMALS are being genetically modified at the Roslin Institute to increase resistance to disease.
As well as creating pigs with incurable human conditions, the scientists are also trying to modify the creatures so they can survive a virus called African swine flu.
Whereas European pigs – the large, meat-producing variety – quickly die from the disease if introduced to Africa, the African variety, the warthog, is resistant.
But the two breeds are unable to mate to produce a large, meat-producing variety that is resistant to the disease.
So instead the Roslin scientists have identified a gene in the African warthog they believe could be responsible for the resistance.
“If you take one of our large, meat-producing animals and put it into Africa, within 24 hours it (will be infected and] will bleed to death, which limits our ability to genetically bring this large, high-producing animal into sub-Saharan subsistence,” said Dr Whitelaw
“The version of the gene the African pigs have, we believe, may be part of the reason they don’t die from this virus.”
The work is still at an early stage and no pigs have yet been born that are resistant.
Dr Whitelaw believes the public will find the use of genetic modification in order to help animals stave off disease less controversial than modifying pigs so that they suffer from incurable human conditions.
“Many people, I presume, would say that making an animal able to resist an infection is good.
“When we go to India we get a whole string of vaccinations and we wouldn’t dare go there without. This is a similar idea.”
However, he still believes it raises complex issues.
“But then you go into issues about what impact bringing in that new type of pig would have on the ecosystem and the society, which are quite complex debates.”
